Phase II Studies of Gemcitabine and Cisplatin in Heavily and Minimally Pretreated Metastatic Breast Cancer

PURPOSE: Cisplatin and gemcitabine have single-agent activity in metastatic breast cancer, and preclinical data support synergy of the combination. Two parallel, phase II trials were conducted to evaluate the response rate, response duration, and toxicities of the combination. Genetic polymorphisms...

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Detalhes bibliográficos
Main Authors: Chew, Helen K., Doroshow, James H., Frankel, Paul, Margolin, Kim A., Somlo, George, Lenz, Heinz-Josef, Gordon, Michael, Zhang, Wu, Yang, Dongyun, Russell, Christy, Spicer, Darcy, Synold, Tim, Bayer, Robert, Hantel, Alexander, Stiff, Patrick J., Tetef, Merry L., Gandara, David R., Albain, Kathy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674003/
https://ncbi.nlm.nih.gov/pubmed/19307510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.4839
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