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Rapamycin conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: implications for the mechanisms of Hsp mRNA translation

Rapamycin inhibits the activity of the target of rapamycin (TOR)-dependent signaling pathway, which has been characterized as one dedicated to translational regulation through modulating cap-dependent translation, involving eIF4E binding protein (eIF4E-BP) or 4E-BP. Results show that rapamycin stron...

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Detalhes bibliográficos
Autor principal: Duncan, Roger F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673887/
https://ncbi.nlm.nih.gov/pubmed/18418733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-008-0024-6
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