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Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors

Sonic hedgehog (Shh) and insulin-like growth factor (IGF) signaling are essential for development of many tissues and are implicated in medulloblastoma, the most common solid pediatric malignancy. Cerebellar granule neuron precursors (CGNPs), proposed cells-of-origin for certain classes of medullobl...

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Bibliografische gegevens
Hoofdauteurs: Parathath, Susana R., Mainwaring, Lori Anne, Fernandez-L, Africa, Campbell, Dane Ohlosson, Kenney, Anna Marie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673703/
https://ncbi.nlm.nih.gov/pubmed/18755774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.022871
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