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Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization

The development of skin carcinomas presently is believed to be correlated with mutations in the p53 tumor suppressor and ras gene as well as with the loss of chromosome 9. We now demonstrate that, in addition, loss of chromosome 15 may be a relevant genetic defect. Reintroduction of an extra copy of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bleuel, Kerstin, Popp, Susanne, Fusenig, Norbert E., Stanbridge, Eric J., Boukamp, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2065
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