Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization

The development of skin carcinomas presently is believed to be correlated with mutations in the p53 tumor suppressor and ras gene as well as with the loss of chromosome 9. We now demonstrate that, in addition, loss of chromosome 15 may be a relevant genetic defect. Reintroduction of an extra copy of...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Bleuel, Kerstin, Popp, Susanne, Fusenig, Norbert E., Stanbridge, Eric J., Boukamp, Petra
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2065
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