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Issues in Noninferiority Trials: The Evidence in Community-Acquired Pneumonia

When investigators hypothesize that experimental interventions provide advantages other than improved effectiveness, they can use noninferiority (NI) trials to determine whether one can rule out the possibility that those interventions have unacceptably worse effectiveness than the standard “active...

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Bibliografiske detaljer
Main Authors: Fleming, Thomas R., Powers, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673530/
https://ncbi.nlm.nih.gov/pubmed/18986275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/591390
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