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Issues in Noninferiority Trials: The Evidence in Community-Acquired Pneumonia

When investigators hypothesize that experimental interventions provide advantages other than improved effectiveness, they can use noninferiority (NI) trials to determine whether one can rule out the possibility that those interventions have unacceptably worse effectiveness than the standard “active...

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Autori principali: Fleming, Thomas R., Powers, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673530/
https://ncbi.nlm.nih.gov/pubmed/18986275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/591390
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