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Drosophila HNF4 Regulates Lipid Mobilization and β-Oxidation
Drosophila HNF4 (dHNF4) is the single ancestral ortholog of a highly conserved subfamily of nuclear receptors that includes two mammalian receptors, HNFα and HNFγ, and 269 members in C. elegans. We show here that dHNF4 null mutant larvae are sensitive to starvation. Starved mutant larvae consume gly...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673486/ https://ncbi.nlm.nih.gov/pubmed/19254568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.01.009 |
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