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Drosophila HNF4 Regulates Lipid Mobilization and β-Oxidation

Drosophila HNF4 (dHNF4) is the single ancestral ortholog of a highly conserved subfamily of nuclear receptors that includes two mammalian receptors, HNFα and HNFγ, and 269 members in C. elegans. We show here that dHNF4 null mutant larvae are sensitive to starvation. Starved mutant larvae consume gly...

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Bibliografiske detaljer
Main Authors: Palanker, Laura, Tennessen, Jason M., Lam, Geanette, Thummel, Carl S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673486/
https://ncbi.nlm.nih.gov/pubmed/19254568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.01.009
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