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The effects of mismatches on hybridization in DNA microarrays: determination of nearest neighbor parameters

Quantifying interactions in DNA microarrays is of central importance for a better understanding of their functioning. Hybridization thermodynamics for nucleic acid strands in aqueous solution can be described by the so-called nearest neighbor model, which estimates the hybridization free energy of a...

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Bibliografische gegevens
Hoofdauteurs: Hooyberghs, J., Van Hummelen, P., Carlon, E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673445/
https://ncbi.nlm.nih.gov/pubmed/19270064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp109
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