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Influence of nearest neighbor sequence on the stability of base pair mismatches in long DNA; determination by temperature-gradient gel electrophoresis.

Temperature-gradient gel electrophoresis (TGGE) was employed to determine the thermal stabilities of 48 DNA fragments that differ by single base pair mismatches. The approach provides a rapid way for studying how specific base mismatches effect the stability of a long DNA fragment. Homologous 373 bp...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ke, S H, Wartell, R M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC310628/
https://ncbi.nlm.nih.gov/pubmed/8255768
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