Novel sequencing strategy for repetitive DNA in a Drosophila BAC clone reveals that the centromeric region of the Y chromosome evolved from a telomere(†)

The centromeric and telomeric heterochromatin of eukaryotic chromosomes is mainly composed of middle-repetitive elements, such as transposable elements and tandemly repeated DNA sequences. Because of this repetitive nature, Whole Genome Shotgun Projects have failed in sequencing these regions. We de...

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Detalhes bibliográficos
Main Authors: Méndez-Lago, María, Wild, Jadwiga, Whitehead, Siobhan L., Tracey, Alan, de Pablos, Beatriz, Rogers, Jane, Szybalski, Waclaw, Villasante, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673431/
https://ncbi.nlm.nih.gov/pubmed/19237394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp085
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