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Conditionally Amplifiable BACs: Switching From Single-Copy to High-Copy Vectors and Genomic Clones
The widely used, very-low-copy BAC (bacterial artificial chromosome) vectors are the mainstay of present genomic research. The principal advantage of BACs is the high stability of inserted clones, but an important disadvantage is the low yield of DNA, both for vectors alone and when carrying genomic...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186656/ https://ncbi.nlm.nih.gov/pubmed/12213781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130502 |
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