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Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis

The RAG proteins initiate V(D)J recombination by mediating synapsis and cleavage of two different antigen receptor gene segments through interactions with their flanking recombination signal sequences (RSS). The protein–DNA complexes that support this process have mainly been studied using RAG–RSS c...

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Bibliografiske detaljer
Main Authors: Kumar, Sushil, Swanson, Patrick C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673416/
https://ncbi.nlm.nih.gov/pubmed/19233873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp047
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