Differential Effect of Extracellular Acidosis on the Release and Dispersal of Soluble and Membrane Proteins Secreted from the Weibel-Palade Body

Proteins secreted from Weibel-Palade bodies (WPBs) play important roles in regulating inflammatory and hemostatic responses. Inflammation is associated with the extracellular acidification of tissues and blood, conditions that can alter the behavior of secreted proteins. The effect of extracellular...

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Main Authors: Babich, Victor, Knipe, Laura, Hewlett, Lindsay, Meli, Athinoula, Dempster, John, Hannah, Matthew J., Carter, Tom
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Mechanisms of Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673312/
https://ncbi.nlm.nih.gov/pubmed/19258324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809235200
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