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Structural organization of Weibel-Palade bodies revealed by cryo-EM of vitrified endothelial cells

In endothelial cells, the multifunctional blood glycoprotein von Willebrand Factor (VWF) is stored for rapid exocytic release in specialized secretory granules called Weibel-Palade bodies (WPBs). Electron cryomicroscopy at the thin periphery of whole, vitrified human umbilical vein endothelial cells...

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Autors principals: Berriman, John A., Li, Sam, Hewlett, Lindsay J., Wasilewski, Sebastian, Kiskin, Fedir N., Carter, Tom, Hannah, Matthew J., Rosenthal, Peter B.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765093/
https://ncbi.nlm.nih.gov/pubmed/19805028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902977106
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