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Molecular Mechanism for SHP2 in Promoting HER2-induced Signaling and Transformation
The Src homology phosphotyrosyl phosphatase 2 (SHP2) plays a positive role in HER2-induced signaling and transformation, but its mechanism of action is poorly understood. Given the significance of HER2 in breast cancer, defining a mechanism for SHP2 in the HER2 signaling pathway is of paramount impo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673291/ https://ncbi.nlm.nih.gov/pubmed/19261604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900020200 |
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