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Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

The Src homology 2-containing phosphotyrosine phosphatase (SHP2) is primarily a positive effector of receptor tyrosine kinase signaling. However, the molecular mechanism by which SHP2 effects its biological function is unknown. In this report, we provide evidence that defines the molecular mechanism...

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Detalhes bibliográficos
Main Authors: Agazie, Yehenew M., Hayman, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC207628/
https://ncbi.nlm.nih.gov/pubmed/14560030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7875-7886.2003
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