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Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling
The Src homology 2-containing phosphotyrosine phosphatase (SHP2) is primarily a positive effector of receptor tyrosine kinase signaling. However, the molecular mechanism by which SHP2 effects its biological function is unknown. In this report, we provide evidence that defines the molecular mechanism...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC207628/ https://ncbi.nlm.nih.gov/pubmed/14560030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7875-7886.2003 |
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