Specific Role of Neuronal Nitric-oxide Synthase when Tethered to the Plasma Membrane Calcium Pump in Regulating the β-Adrenergic Signal in the Myocardium

The cardiac neuronal nitric-oxide synthase (nNOS) has been described as a modulator of cardiac contractility. We have demonstrated previously that isoform 4b of the sarcolemmal calcium pump (PMCA4b) binds to nNOS in the heart and that this complex regulates β-adrenergic signal transmission in vivo....

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Hlavní autoři: Mohamed, Tamer M. A., Oceandy, Delvac, Prehar, Sukhpal, Alatwi, Nasser, Hegab, Zeinab, Baudoin, Florence M., Pickard, Adam, Zaki, Aly O., Nadif, Raja, Cartwright, Elizabeth J., Neyses, Ludwig
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673278/
https://ncbi.nlm.nih.gov/pubmed/19278978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809112200
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