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Targeted Disruption of ROCK1 Causes Insulin Resistance in Vivo

Insulin signaling is essential for normal glucose homeostasis. Rho-kinase (ROCK) isoforms have been shown to participate in insulin signaling and glucose metabolism in cultured cell lines. To investigate the physiological role of ROCK1 in the regulation of whole body glucose homeostasis and insulin...

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Detalhes bibliográficos
Main Authors: Lee, Dae Ho, Shi, Jianjian, Jeoung, Nam Ho, Kim, Min Seon, Zabolotny, Janice M., Lee, Sam W., White, Morris F., Wei, Lei, Kim, Young-Bum
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673246/
https://ncbi.nlm.nih.gov/pubmed/19276091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C900014200
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