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In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes
To determine whether serine/threonine ROCK1 is activated by insulin in vivo in humans and whether impaired activation of ROCK1 could play a role in the pathogenesis of insulin resistance, we measured the activity of ROCK1 and the protein content of the Rho family in vastus lateralis muscle of lean,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064006/ https://ncbi.nlm.nih.gov/pubmed/21189360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00538.2010 |
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