Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

Although nutrients, including amino acids and their metabolites such as serotonin (5-HT), are strong modulators of anxiety-related behavior, the metabolic pathway(s) responsible for this physiological modulation is not fully understood. Regarding tryptophan (Trp), the initial rate-limiting enzymes f...

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Bibliographische Detailangaben
Hauptverfasser: Kanai, Masaaki, Funakoshi, Hiroshi, Takahashi, Hisaaki, Hayakawa, Tomoko, Mizuno, Shinya, Matsumoto, Kunio, Nakamura, Toshikazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673217/
https://ncbi.nlm.nih.gov/pubmed/19323847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-8
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