Recombinant human activated protein C inhibits integrin-mediated neutrophil migration

Integrin-mediated cell migration is central to many biologic and pathologic processes. During inflammation, tissue injury results from excessive infiltration and sequestration of activated leukocytes. Recombinant human activated protein C (rhAPC) has been shown to protect patients with severe sepsis...

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Autori principali: Elphick, Gwendolyn F., Sarangi, Pranita P., Hyun, Young-Min, Hollenbaugh, Joseph A., Ayala, Alfred, Biffl, Walter L., Chung, Hung-Li, Rezaie, Alireza R., McGrath, James L., Topham, David J., Reichner, Jonathan S., Kim, Minsoo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Phagocytes, Granulocytes, and Myelopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673129/
https://ncbi.nlm.nih.gov/pubmed/19244161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-180968
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