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Expanded hammerhead ribozymes containing addressable three-way junctions
Recently, hammerhead ribozyme (HHR) motifs have been utilized as powerful tools for gene regulation. Here we present a novel design of expanded full-length HHRs that allows attaching additional functionalities to the ribozyme. These features allowed us to construct a very efficient artificial ribosw...
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| Asıl Yazarlar: | , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673082/ https://ncbi.nlm.nih.gov/pubmed/19304923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1220309 |
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