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Cordycepin interferes with 3′ end formation in yeast independently of its potential to terminate RNA chain elongation

Cordycepin (3′ deoxyadenosine) is a biologically active compound that, when incorporated during RNA synthesis in vitro, provokes chain termination due to the absence of a 3′ hydroxyl moiety. We were interested in the effects mediated by this drug in vivo and analyzed its impact on RNA metabolism of...

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Bibliografiske detaljer
Main Authors: Holbein, Sandra, Wengi, Agnieszka, Decourty, Laurence, Freimoser, Florian M., Jacquier, Alain, Dichtl, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673080/
https://ncbi.nlm.nih.gov/pubmed/19324962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1458909
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