Computational and analytical framework for small RNA profiling by high-throughput sequencing

The advent of high-throughput sequencing (HTS) methods has enabled direct approaches to quantitatively profile small RNA populations. However, these methods have been limited by several factors, including representational artifacts and lack of established statistical methods of analysis. Furthermore...

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Autori principali: Fahlgren, Noah, Sullivan, Christopher M., Kasschau, Kristin D., Chapman, Elisabeth J., Cumbie, Jason S., Montgomery, Taiowa A., Gilbert, Sunny D., Dasenko, Mark, Backman, Tyler W.H., Givan, Scott A., Carrington, James C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2009
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673065/
https://ncbi.nlm.nih.gov/pubmed/19307293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1473809
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