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Computational and analytical framework for small RNA profiling by high-throughput sequencing

The advent of high-throughput sequencing (HTS) methods has enabled direct approaches to quantitatively profile small RNA populations. However, these methods have been limited by several factors, including representational artifacts and lack of established statistical methods of analysis. Furthermore...

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Bibliographic Details
Main Authors: Fahlgren, Noah, Sullivan, Christopher M., Kasschau, Kristin D., Chapman, Elisabeth J., Cumbie, Jason S., Montgomery, Taiowa A., Gilbert, Sunny D., Dasenko, Mark, Backman, Tyler W.H., Givan, Scott A., Carrington, James C.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673065/
https://ncbi.nlm.nih.gov/pubmed/19307293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1473809
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