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Involution of Collagen-Induced Arthritis with an Angiogenesis Inhibitor, PPI-2458
Pannus formation, in both rheumatoid arthritis (RA) and collagen-induced arthritis (CIA), is angiogenesis-dependent. PPI-2458 [(1R)-1-carbamoyl-2-methyl]-carbamic acid-(3R,3S,5S, 6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-but-2-enyl)oxiranyl]-1-oxaspiro(2(*)5)oct-6-yl ester], a new fumagillin der...
Guardat en:
| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672877/ https://ncbi.nlm.nih.gov/pubmed/19218530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.148478 |
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