Regulator of G Protein Signaling Protein Suppression of Gα(o) Protein-Mediated α(2A) Adrenergic Receptor Inhibition of Mouse Hippocampal CA3 Epileptiform Activity

Activation of G protein-coupled α(2) adrenergic receptors (ARs) inhibits epileptiform activity in the hippocampal CA3 region. The specific mechanism underlying this action is unclear. This study investigated which subtype(s) of α(2)ARs and G proteins (Gα(o) or Gα(i)) are involved in this response us...

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Detalhes bibliográficos
Main Authors: Goldenstein, Brianna L., Nelson, Brian W., Xu, Ke, Luger, Elizabeth J., Pribula, Jacquline A., Wald, Jenna M., O'Shea, Lorraine A., Weinshenker, David, Charbeneau, Raelene A., Huang, Xinyan, Neubig, Richard R., Doze, Van A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672807/
https://ncbi.nlm.nih.gov/pubmed/19225179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.054296
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