Global Functional Atlas of Escherichia coli Encompassing Previously Uncharacterized Proteins

One-third of the 4,225 protein-coding genes of Escherichia coli K-12 remain functionally unannotated (orphans). Many map to distant clades such as Archaea, suggesting involvement in basic prokaryotic traits, whereas others appear restricted to E. coli, including pathogenic strains. To elucidate the...

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Autori principali: Hu, Pingzhao, Janga, Sarath Chandra, Babu, Mohan, Díaz-Mejía, J. Javier, Butland, Gareth, Yang, Wenhong, Pogoutse, Oxana, Guo, Xinghua, Phanse, Sadhna, Wong, Peter, Chandran, Shamanta, Christopoulos, Constantine, Nazarians-Armavil, Anaies, Nasseri, Negin Karimi, Musso, Gabriel, Ali, Mehrab, Nazemof, Nazila, Eroukova, Veronika, Golshani, Ashkan, Paccanaro, Alberto, Greenblatt, Jack F, Moreno-Hagelsieb, Gabriel, Emili, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672614/
https://ncbi.nlm.nih.gov/pubmed/19402753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000096
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