טוען...
The actin regulator coronin-1A is mutated in a thymic egress deficient mouse strain and in a T(−)B(+)NK(+) SCID patient
Mice carrying the recessive peripheral T cell deficiency (Ptcd) locus have a block in thymic egress but the mechanism responsible is undefined. Here we found that Ptcd T cells have an intrinsic migration defect, impaired lymphoid tissue trafficking and irregularly shaped protrusions. Characterizatio...
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| Main Authors: | , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672406/ https://ncbi.nlm.nih.gov/pubmed/18836449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1662 |
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