טוען...

The actin regulator coronin-1A is mutated in a thymic egress deficient mouse strain and in a T(−)B(+)NK(+) SCID patient

Mice carrying the recessive peripheral T cell deficiency (Ptcd) locus have a block in thymic egress but the mechanism responsible is undefined. Here we found that Ptcd T cells have an intrinsic migration defect, impaired lymphoid tissue trafficking and irregularly shaped protrusions. Characterizatio...

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מידע ביבליוגרפי
Main Authors: Shiow, Lawrence R., Roadcap, David W., Paris, Kenneth, Watson, Susan R., Grigorova, Irina L., Lebet, Tonya, An, Jinping, Xu, Ying, Jenne, Craig N., Föger, Niko, Sorensen, Ricardo U., Goodnow, Christopher C., Bear, James E., Puck, Jennifer M., Cyster, Jason G.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672406/
https://ncbi.nlm.nih.gov/pubmed/18836449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1662
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