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Neuropathology and Therapeutic Intervention in Spinal and Bulbar Muscular Atrophy

Spinal and bulbar muscular atrophy (SBMA) is a hereditary motor neuron disease caused by the expansion of a polyglutamine tract in the androgen receptor (AR). The histopathological finding in SBMA is loss of lower motor neurons in the anterior horn of the spinal cord as well as in the brainstem moto...

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Detalhes bibliográficos
Main Authors: Banno, Haruhiko, Katsuno, Masahisa, Suzuki, Keisuke, Tanaka, Fumiaki, Sobue, Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672015/
https://ncbi.nlm.nih.gov/pubmed/19399234
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