Human Uterine Smooth Muscle and Leiomyoma Cells Differ in Their Rapid 17β-Estradiol Signaling: Implications for Proliferation

Uterine leiomyomas, benign uterine smooth muscle tumors that affect 30% of reproductive-aged women, are a significant health concern. The initiation event for these tumors is unclear, but 17β-estradiol (E2) is an established promoter of leiomyoma growth. E2 not only alters transcription of E2-regula...

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Main Authors: Nierth-Simpson, Erica N., Martin, Melvenia M., Chiang, Tung-Chin, Melnik, Lilia I., Rhodes, Lyndsay V., Muir, Shannon E., Burow, Matthew E., McLachlan, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671893/
https://ncbi.nlm.nih.gov/pubmed/19179429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0224
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