DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms.

Endocrine-disrupting organochlorines, such as the pesticide dichlorodiphenyltrichloroethane (DDT), bind to and activate estrogen receptors (ERs), thereby eliciting estrogen-like effects. Although ERs function predominantly through activation of transcription via estrogen-responsive elements, both ER...

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Detalhes bibliográficos
Main Authors: Frigo, Daniel E, Burow, Matthew E, Mitchell, Kamron A, Chiang, Tung-Chin, McLachlan, John A
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1241112/
https://ncbi.nlm.nih.gov/pubmed/12460804
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