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DIMORPHIC EFFECTS OF NOTCH SIGNALING IN BONE HOMEOSTASIS

Notch signaling is a central mechanism for controlling embryogenesis. However, its in vivo function during mesenchymal cell differentiation, and specifically, in bone homeostasis remains largely unknown. Here, we show that osteoblast-specific gain of Notch function causes severe osteosclerosis due t...

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Detalhes bibliográficos
Main Authors: Engin, Feyza, Yao, Zhenqiang, Yang, Tao, Zhou, Guang, Bertin, Terry, Jiang, Ming Ming, Chen, Yuqing, Wang, Lisa, Zheng, Hui, Sutton, Richard E., Boyce, Brendan F., Lee, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671578/
https://ncbi.nlm.nih.gov/pubmed/18297084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1712
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