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Nicotine-induced Disturbances of Meiotic Maturation in Cultured Mouse Oocytes: Alterations of Spindle Integrity and Chromosome Alignment

We investigated whether nicotine exposure in vitro of mouse oocytes affects spindle and chromosome function during meiotic maturation (M-I and M-II). Oocytes in germinal vesicle (GV) stage were cultured in nicotine for 8 h or for 16 h, to assess effects in M-I and in metaphase II (M-II). The latter...

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Detalhes bibliográficos
Main Authors: Zenzes, Maria Teresa, Bielecki, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671544/
https://ncbi.nlm.nih.gov/pubmed/19570282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1617-9625-2-3-151
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