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Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment

Mitotic spindles assemble from two centrosomes, which are major microtubule‐organizing centers (MTOCs) that contain centrioles. Meiotic spindles in oocytes, however, lack centrioles. In mouse oocytes, spindle microtubules are nucleated from multiple acentriolar MTOCs that are sorted and clustered pr...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Bennabi, Isma, Quéguiner, Isabelle, Kolano, Agnieszka, Boudier, Thomas, Mailly, Philippe, Verlhac, Marie‐Hélène, Terret, Marie‐Emilie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797964/
https://ncbi.nlm.nih.gov/pubmed/29330318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745225
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