Oxidative Stress-Mediated Mitochondrial Dysfunction Contributes to Angiotensin II-Induced Nonalcoholic Fatty Liver Disease in Transgenic Ren2 Rats

Emerging evidence indicates that impaired mitochondrial fatty acid β-oxidation plays a key role in liver steatosis. We have recently demonstrated that increased angiotensin (ANG) II causes progressive hepatic steatosis associated with oxidative stress; however, the underlying mechanisms remain uncle...

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Main Authors: Wei, Yongzhong, Clark, Suzanne E., Thyfault, John P., Uptergrove, Grace M.E., Li, Wenhan, Whaley-Connell, Adam T., Ferrario, Carlos M., Sowers, James R., Ibdah, Jamal A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2009
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671364/
https://ncbi.nlm.nih.gov/pubmed/19246643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080697
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