Protective Role of Endogenous Gangliosides for Lysosomal Pathology in a Cellular Model of Synucleinopathies

Gangliosides may be involved in the pathogenesis of Parkinson’s disease and related disorders, although the precise mechanisms governing this involvement remain unknown. In this study, we determined whether changes in endogenous ganglioside levels affect lysosomal pathology in a cellular model of sy...

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Bibliografiske detaljer
Main Authors: Wei, Jianshe, Fujita, Masayo, Nakai, Masaaki, Waragai, Masaaki, Sekigawa, Akio, Sugama, Shuei, Takenouchi, Takato, Masliah, Eliezer, Hashimoto, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2009
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671277/
https://ncbi.nlm.nih.gov/pubmed/19349362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080680
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