Protective Role of Endogenous Gangliosides for Lysosomal Pathology in a Cellular Model of Synucleinopathies

Gangliosides may be involved in the pathogenesis of Parkinson’s disease and related disorders, although the precise mechanisms governing this involvement remain unknown. In this study, we determined whether changes in endogenous ganglioside levels affect lysosomal pathology in a cellular model of sy...

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Main Authors: Wei, Jianshe, Fujita, Masayo, Nakai, Masaaki, Waragai, Masaaki, Sekigawa, Akio, Sugama, Shuei, Takenouchi, Takato, Masliah, Eliezer, Hashimoto, Makoto
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671277/
https://ncbi.nlm.nih.gov/pubmed/19349362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080680
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