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Protective Role of Endogenous Gangliosides for Lysosomal Pathology in a Cellular Model of Synucleinopathies

Gangliosides may be involved in the pathogenesis of Parkinson’s disease and related disorders, although the precise mechanisms governing this involvement remain unknown. In this study, we determined whether changes in endogenous ganglioside levels affect lysosomal pathology in a cellular model of sy...

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Main Authors: Wei, Jianshe, Fujita, Masayo, Nakai, Masaaki, Waragai, Masaaki, Sekigawa, Akio, Sugama, Shuei, Takenouchi, Takato, Masliah, Eliezer, Hashimoto, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671277/
https://ncbi.nlm.nih.gov/pubmed/19349362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080680
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