Global Levels of Histone Modifications Predict Prognosis in Different Cancers

Cancer cells exhibit alterations in histone modification patterns at individual genes and globally at the level of single nuclei in individual cells. We demonstrated previously that lower global/cellular levels of histone H3 lysine 4 dimethylation (H3K4me2) and H3K18 acetylation (ac) predict a highe...

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Detalhes bibliográficos
Main Authors: Seligson, David B., Horvath, Steve, McBrian, Matthew A., Mah, Vei, Yu, Hong, Tze, Sheila, Wang, Qun, Chia, David, Goodglick, Lee, Kurdistani, Siavash K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671251/
https://ncbi.nlm.nih.gov/pubmed/19349354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080874
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