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Global Levels of Histone Modifications Predict Prognosis in Different Cancers
Cancer cells exhibit alterations in histone modification patterns at individual genes and globally at the level of single nuclei in individual cells. We demonstrated previously that lower global/cellular levels of histone H3 lysine 4 dimethylation (H3K4me2) and H3K18 acetylation (ac) predict a highe...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671251/ https://ncbi.nlm.nih.gov/pubmed/19349354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080874 |
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