Histone H3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells

Lysine 56 acetylation in the helical core of histone H3 opens yeast chromatin and enables histone gene transcription, DNA replication, DNA repair, and prevents epigenetic silencing. While K56Ac is globally abundant in yeast and flies its presence has been uncertain in mammals. We show here using mas...

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Main Authors: Xie, Wei, Song, Chunying, Young, Nicolas L., Sperling, Adam, Xu, Feng, Sridharan, Rupa, Conway, Anne, Garcia, Benjamin A., Plath, Kathrin, Clark, Amander, Grunstein, Michael
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671231/
https://ncbi.nlm.nih.gov/pubmed/19250903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.02.004
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