Co-Regulation and Interdependence of the Mammalian Epidermal Permeability and Antimicrobial Barriers

Human epidermis elaborates two small cationic, highly hydrophobic antimicrobial peptides (AMP), β-defensin 2 (hBD2), and the carboxypeptide cleavage product of human cathelicidin (hCAP18), LL-37, which are co-packaged along with lipids within epidermal lamellar bodies (LBs) before their secretion. B...

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Detalhes bibliográficos
Main Authors: Aberg, Karin M., Man, Mao-Qiang, Gallo, Richard L., Ganz, Tomas, Crumrine, Debra, Brown, Barbara E., Choi, Eung-Ho, Kim, Dong-Kun, Schröder, Jens M., Feingold, Kenneth R., Elias, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671223/
https://ncbi.nlm.nih.gov/pubmed/17943185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5701099
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