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Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia : Implications for the Pathogenesis of Psoriasis

Primary abnormalities in permeability barrier function appear to underlie atopic dermatitis and epidermal trauma; a concomitant barrier dysfunction could also drive other inflammatory dermatoses, including psoriasis. Central to this outside-inside view of disease pathogenesis is the epidermal genera...

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Detalhes bibliográficos
Main Authors: Elias, Peter M., Arbiser, Jack, Brown, Barbara E., Rossiter, Heidemarie, Man, Mao-Qiang, Cerimele, Francesca, Crumrine, Debra, Gunathilake, Roshan, Choi, Eung Ho, Uchida, Yoshikazu, Tschachler, Erwin, Feingold, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527083/
https://ncbi.nlm.nih.gov/pubmed/18688025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080088
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