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The neuroprotective factor Wld(s) fails to mitigate distal axonal and neuromuscular junction (NMJ) defects in mouse models of spinal muscular atrophy

Spinal muscular atrophy (SMA) is a common autosomal recessive neurodegenerative disorder in humans. Amongst the earliest signs of neurodegeneration are severe and progressive defects of the neuromuscular synapse. These defects, characterized by poor terminal arborization and immature motor endplates...

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Bibliografske podrobnosti
Main Authors: Kariya, Shingo, Mauricio, Rina, Dai, Ya, Monani, Umrao R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671206/
https://ncbi.nlm.nih.gov/pubmed/19010394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.10.107
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