Polymorphism Located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 Haplotype Confer Susceptibility to CNS Hypersomnias (Essential Hypersomnia)

BACKGROUND: SNP rs5770917 located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 haplotype were previously identified as susceptibility loci for narcolepsy with cataplexy. This study was conducted in order to investigate whether these genetic markers are associated with Japanese CNS hypersomnia...

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Autori principali: Miyagawa, Taku, Honda, Makoto, Kawashima, Minae, Shimada, Mihoko, Tanaka, Susumu, Honda, Yutaka, Tokunaga, Katsushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671172/
https://ncbi.nlm.nih.gov/pubmed/19404393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005394
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