ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis

Apoptosis and inflammation generally exert opposite effects on tumorigenesis: apoptosis serves as a barrier to tumour initiation, whereas inflammation promotes tumorigenesis. Although both events are induced by various common stressors, relatively little is known about the stress-induced signalling...

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Hauptverfasser: Iriyama, Takayuki, Takeda, Kohsuke, Nakamura, Hiromi, Morimoto, Yoshifumi, Kuroiwa, Takumi, Mizukami, Junya, Umeda, Tsuyoshi, Noguchi, Takuya, Naguro, Isao, Nishitoh, Hideki, Saegusa, Kaoru, Tobiume, Kei, Homma, Toshiki, Shimada, Yutaka, Tsuda, Hitoshi, Aiko, Satoshi, Imoto, Issei, Inazawa, Johji, Chida, Kazuhiro, Kamei, Yoshimasa, Kozuma, Shiro, Taketani, Yuji, Matsuzawa, Atsushi, Ichijo, Hidenori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670860/
https://ncbi.nlm.nih.gov/pubmed/19214184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.32
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