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alpha-Sarcin catalytic activity is not required for cytotoxicity
BACKGROUND: α-Sarcin is a protein toxin produced by Aspergillus giganteus. It belongs to a family of cytotoxic ribonucleases that inactivate the ribosome and inhibit protein synthesis. α-Sarcin cleaves a single phosphodiester bond within the RNA backbone of the large ribosomal subunit, which makes t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670844/ https://ncbi.nlm.nih.gov/pubmed/19344516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-10-9 |
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