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Lysophosphatidyl choline modulates mechanosensitive L-type Ca(2+) current in circular smooth muscle cells from human jejunum

The L-type Ca(2+) channel expressed in gastrointestinal smooth muscle is mechanosensitive. Direct membrane stretch and shear stress result in increased Ca(2+) entry into the cell. The mechanism for mechanosensitivity is not known, and mechanosensitivity is not dependent on an intact cytoskeleton. Th...

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Main Authors: Kraichely, Robert E., Strege, Peter R., Sarr, Michael G., Kendrick, Michael L., Farrugia, Gianrico
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670668/
https://ncbi.nlm.nih.gov/pubmed/19179622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90610.2008
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