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CpG Oligonucleotides Enhance Proliferative and Effector Responses of B Cells in HIV-Infected Individuals

Stimulation through TLR represents a new therapeutic approach for enhancing Ab responses to vaccination. Considering that Ab responses are decreased in HIV disease and that B cells express TLR9 and respond to TLR9 agonists, we investigated the responsiveness of B cell subpopulations from HIV-infecte...

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Main Authors: Malaspina, Angela, Moir, Susan, DiPoto, Angela C., Ho, Jason, Wang, Wei, Roby, Gregg, O’Shea, Marie A., Fauci, Anthony S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670450/
https://ncbi.nlm.nih.gov/pubmed/18606673
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